Tools

Three interactive teaching tools, all running entirely in your browser — nothing is uploaded, nothing is installed, and no sequence ever leaves your machine. Start with the DNA Sequence Lab for quick analysis, take the sequence into the Protein Lab, then step through an illustration of a CRISPR‑Cas9 edit. Free to use, including in teaching.

DNA Sequence Lab

Paste a DNA sequence to analyse it, scan for SpCas9 targets, check for Golden Gate Type IIS sites, or run a local alignment.

Protein Lab

Translate DNA and find ORFs, compute physicochemical properties (MW, pI, charge, GRAVY, extinction coefficient), plot Kyte–Doolittle hydropathy, and scan for common sequence motifs — all in the browser.

Illustration of CRISPR‑Cas9 editing, step by step

Pick a target gene and an edit type, then run it. The guide RNA anneals to the protospacer, Cas cuts 3 bp upstream of the NGG PAM, and the sequence is repaired with a lesion — an indel (knockout) or a substitution — with the bases colour-coded throughout.